FOR RESEARCH USE ONLY
Semax

CHEMICAL PROPERTIES

CAS NUMBER80714-61-0
MOLECULAR WEIGHT802.92 g/mol
MOLECULAR FORMULAC₃₇H₅₁N₉O₁₀S

PHYSICAL PROPERTIES

APPEARANCEWhite lyophilized powder in sealed borosilicate glass vial.
SEQUENCEMet-Glu-His-Phe-Pro-Gly-Pro

Semax

Semax is a synthetic heptapeptide analogue of the ACTH(4-7) fragment, developed as a stable, bioavailable derivative for research purposes. It has been studied extensively in neurological research contexts, particularly in relation to BDNF expression, neuroprotection, and cognitive function models.

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LOT NUMBERLMO-0626-SMX-019
REPORT NO.RPT-20013
HPLC PURITY98.40%

7× Independently Tested

HPLC PurityIndependent lab
IdentitySequence confirmed
Net ContentExact mg verified
SterilityContamination-free
EndotoxinsLAL tested
Heavy MetalsICP-MS screened
Batch ConsistencyLot-to-lot stability
TESTED

RESEARCH USE ONLY

This compound is sold strictly for in vitro research and laboratory use. Not for human or animal consumption. Not a drug, food, or supplement. By purchasing you confirm you are a qualified researcher and will use this compound in compliance with all applicable laws. Must be 21 or older.

RESEARCH

The Peptide Semax Affects the Expression of Genes Related to the Immune and Vascular Systems in Rat Brain Focal Ischaemia: Genome-Wide Transcriptional Analysis
Medvedeva EV, Dmitrieva VG, Povarova OV, et al. · BMC Genomics · 2014
Genome-wide study showing Semax modulates neurotrophic factor gene expression, BDNF receptor upregulation, and vascular-immune pathway activity in ischaemic brain tissue.
PMID 24529074
Mechanisms of Semax Action in Neuroprotection: Regulation of Antioxidant Pathways and Gene Expression
Medvedev AE, et al. · Bulletin of Experimental Biology and Medicine · 2014
Characterises Semax neuroprotective activity via antioxidant enzyme upregulation, mitochondrial stabilisation under calcium stress, and inhibition of nitric oxide synthesis.
PMID 24770788

LAB RESULTS

LOT LMO-0626-SMX-019 · CURRENT

Certificate of Analysis

PURITY
98.40%
CAS
80714-61-0
MW
802.92 g/mol
APPEARANCE
White lyophilized powder in sealed borosilicate glass vial.
VERIFIED

Third-Party Report

TESTING LABIndependent Analytics LLC
TEST DATEJanuary 2025
METHODS USED
HPLCMSAAA
RESEARCH APPLICATIONS

What the literature covers.

  • BDNF and neurotrophin upregulation studies in neuronal models
  • ACTH(4-7) fragment receptor binding and neuropeptide research
  • Neuroprotection mechanism studies in ischemia and oxidative stress models
  • Cognitive function and memory pathway research in vitro

All compounds sold by Lumo are intended strictly for in vitro research and laboratory use only. These products are NOT intended for human consumption, medical, veterinary, or household use. By purchasing from Lumo, you acknowledge that you are a qualified researcher or institution and will use these products solely for research purposes in compliance with all applicable laws and regulations.

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