FOR RESEARCH USE ONLY
MOTS-c

CHEMICAL PROPERTIES

CAS NUMBER1468720-74-2
MOLECULAR WEIGHT2174.76 g/mol
MOLECULAR FORMULAC₁₀₁H₁₇₄N₃₄O₃₂S₂

PHYSICAL PROPERTIES

APPEARANCEWhite lyophilized powder in sealed borosilicate glass vial.
SEQUENCEMet-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg

MOTS-c

MOTS-c is a 16 amino acid peptide encoded by the mitochondrial 12S rRNA gene. Studied for its role in metabolic homeostasis, AMPK activation, and age-related physical decline.

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LOT NUMBERLMO-0626-MTS-017
REPORT NO.RPT-20019
HPLC PURITY98.50%

7× Independently Tested

HPLC PurityIndependent lab
IdentitySequence confirmed
Net ContentExact mg verified
SterilityContamination-free
EndotoxinsLAL tested
Heavy MetalsICP-MS screened
Batch ConsistencyLot-to-lot stability
TESTED

RESEARCH USE ONLY

This compound is sold strictly for in vitro research and laboratory use. Not for human or animal consumption. Not a drug, food, or supplement. By purchasing you confirm you are a qualified researcher and will use this compound in compliance with all applicable laws. Must be 21 or older.

RESEARCH

A Mitochondrial-Derived Peptide MOTS-c Regulates Glucose and Fatty Acid Metabolism
Lee C, Zeng J, Drew BG, et al. · Cell Metabolism · 2015
Discovery paper identifying MOTS-c as a mitochondrially encoded peptide that activates AMPK, improves insulin sensitivity, and reduces obesity and metabolic dysfunction in mice.
PMID 25738459
MOTS-c: A Novel Mitochondrial-Derived Peptide Regulating Muscle and Fat Metabolism
Lee C, Kim KH, Cohen P. · Free Radical Biology & Medicine · 2016
Reviews MOTS-c biology including its nuclear translocation under stress, AMPK-mediated metabolic reprogramming, and implications for exercise physiology and age-related metabolic decline.
PMID 27216708

LAB RESULTS

LOT LMO-0626-MTS-017 · CURRENT

Certificate of Analysis

PURITY
98.50%
CAS
1468720-74-2
MW
2174.76 g/mol
APPEARANCE
White lyophilized powder in sealed borosilicate glass vial.
VERIFIED

Third-Party Report

TESTING LABIndependent Analytics LLC
TEST DATEJanuary 2025
METHODS USED
HPLCMSAAA
RESEARCH APPLICATIONS

What the literature covers.

  • Mitochondrially encoded peptide studied for AMPK activation and metabolic regulation
  • Investigated for insulin sensitivity improvement in obesity research models
  • Evaluated as exercise-induced regulator of age-dependent physical decline
  • Studied for nuclear translocation under metabolic stress conditions

All compounds sold by Lumo are intended strictly for in vitro research and laboratory use only. These products are NOT intended for human consumption, medical, veterinary, or household use. By purchasing from Lumo, you acknowledge that you are a qualified researcher or institution and will use these products solely for research purposes in compliance with all applicable laws and regulations.

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Research Use Only · Not for Human Consumption · For Laboratory Research Purposes Only

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