⚠ FOR RESEARCH USE ONLY
KPV

CHEMICAL PROPERTIES

CAS NUMBER13588-25-1
MOLECULAR WEIGHT326.35 g/mol
MOLECULAR FORMULAC₁₄H₂₂N₄O₅

PHYSICAL PROPERTIES

APPEARANCEWhite lyophilized powder in sealed borosilicate glass vial.
SEQUENCELys-Pro-Val
Tissue Repair Research

KPV

KPV is a tripeptide (Lys-Pro-Val) derived from the C-terminal region of alpha-MSH. Studied in preclinical models for its anti-inflammatory and gut-protective properties.

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LOT NUMBERLMO-0626-KPV-008
REPORT NO.RPT-20017
HPLC PURITY98.50%

7× Independently Tested

HPLC PurityIndependent lab
IdentitySequence confirmed
Net ContentExact mg verified
SterilityContamination-free
EndotoxinsLAL tested
Heavy MetalsICP-MS screened
Batch ConsistencyLot-to-lot stability
7×
TESTED
⚠

RESEARCH USE ONLY

This compound is sold strictly for in vitro research and laboratory use. Not for human or animal consumption. Not a drug, food, or supplement. By purchasing you confirm you are a qualified researcher and will use this compound in compliance with all applicable laws. Must be 21 or older.

RESEARCH

PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation
Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al. · Gastroenterology · 2008
Demonstrates KPV inhibits NF-kB and MAP kinase inflammatory signalling via PepT1-mediated cellular uptake, and reduces incidence of DSS- and TNBS-induced colitis in mice through oral administration.
PMID 18061177
Dissection of the Anti-Inflammatory Effect of the Core and C-Terminal (KPV) Alpha-MSH Peptides
Getting SJ, Allcock GH, Flower R, Perretti M. · Journal of Pharmacology and Experimental Therapeutics · 2003
Shows KPV reduces polymorphonuclear leukocyte accumulation in a crystal-induced peritonitis model via a non-melanocortin-receptor pathway, distinguishing its mechanism from core alpha-MSH peptides.
PMID 12750433
Antimicrobial Effects of Alpha-MSH Peptides
Cutuli M, Cristiani S, Lipton JM, Catania A. · Journal of Leukocyte Biology · 2000
Demonstrates that alpha-MSH and its C-terminal tripeptide KPV exhibit antimicrobial activity against S. aureus and C. albicans across a broad concentration range including physiological picomolar levels.
PMID 10670585

LAB RESULTS

LOT LMO-0626-KPV-008 · CURRENT

Certificate of Analysis

PURITY
98.50%
CAS
13588-25-1
MW
326.35 g/mol
APPEARANCE
White lyophilized powder in sealed borosilicate glass vial.
VERIFIED

Third-Party Report

TESTING LABIndependent Analytics LLC
TEST DATEJanuary 2025
METHODS USED
HPLCMSAAA
RESEARCH APPLICATIONS

What the literature covers.

  • ●Studied for anti-inflammatory activity via NF-kB pathway modulation
  • ●Investigated for gut epithelial barrier protection in colitis models
  • ●Evaluated for cytokine suppression in inflammatory disease research
  • ●Alpha-MSH C-terminal fragment studied for localised tissue protection

All compounds sold by Lumo are intended strictly for in vitro research and laboratory use only. These products are NOT intended for human consumption, medical, veterinary, or household use. By purchasing from Lumo, you acknowledge that you are a qualified researcher or institution and will use these products solely for research purposes in compliance with all applicable laws and regulations.

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