⚠ FOR RESEARCH USE ONLY
IGF-1 LR3

CHEMICAL PROPERTIES

CAS NUMBER946870-92-4
MOLECULAR WEIGHT9117.60 g/mol
MOLECULAR FORMULAC₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉

PHYSICAL PROPERTIES

APPEARANCEWhite lyophilized powder in sealed borosilicate glass vial.
SEQUENCEArg-Ile-Val-Glu-Gln-Cys-Cys-Thr-Ser-Ile-Cys-Ser-Leu-Tyr-Gln-Leu-Glu-Asn-Tyr-Cys-Asn
Secretagogue Research

IGF-1 LR3

IGF-1 LR3 is an 83-amino-acid long-arginine variant of insulin-like growth factor 1, supplied lyophilized, ≥99.809% purity by HPLC. For in-vitro receptor binding assays and analytical reference use. Not for use in any living organism.

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LOT NUMBERLMO-0626-IGF-020
REPORT NO.KVR-2026-5B595F
HPLC PURITY99.809%

Third-Party Verified

HPLC PurityIndependent lab
IdentitySequence confirmed
ContentExact mg verified
✓
VERIFIED
⚠

RESEARCH USE ONLY

This compound is sold strictly for in vitro research and laboratory use. Not for human or animal consumption. Not a drug, food, or supplement. By purchasing you confirm you are a qualified researcher and will use this compound in compliance with all applicable laws. Must be 21 or older.

RESEARCH

Long R3 Insulin-Like Growth Factor-I (IGF-I) Infusion Stimulates Organ Growth But Reduces Plasma IGF-I, IGF-II and IGF Binding Protein Concentrations
Conlon MA, Tomas FM, Owens PC, et al. · Journal of Endocrinology · 1995
Characterises Long R3 IGF-1 infusion effects on the endocrine axis in guinea pig models, confirming reduced binding protein sequestration compared to native IGF-1.
PMID 7561636
Long [R3] Insulin-Like Growth Factor-I Reduces Growth, Plasma Growth Hormone, IGF Binding Protein-3 and Endogenous IGF-I Concentrations in Pigs
Dunaiski V, Belford DA. · Journal of Endocrinology · 1997
In vivo large animal study characterising the systemic effects of Long R3 IGF-1 administration on the endogenous GH/IGF-1 axis and IGF binding protein regulation.
PMID 9488001
Insulin-Like Growth Factor-I (IGF-I) and Especially IGF-I Variants in Dexamethasone-Treated Rats
Tomas FM, Knowles SE, Owens PC, et al. · Biochemical Journal · 1992
Foundational study describing the Long R3 IGF-1 analogue and documenting its dramatically reduced IGFBP binding affinity compared to native IGF-1, establishing the pharmacokinetic rationale for the LR3 modification.
PMID 1371669

LAB RESULTS

LOT LMO-0626-IGF-020 · CURRENT

Certificate of Analysis

PURITY
99.809%
CAS
946870-92-4
MW
9117.60 g/mol
APPEARANCE
White lyophilized powder in sealed borosilicate glass vial.
VERIFIED
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Third-Party Report

TESTING LABKovera Labs
TEST DATE08/16/2026
METHODS USED
HPLCMSAAA
↓ VIEW REPORT · ZCLVPPF
RESEARCH APPLICATIONS

What the literature covers.

  • ●Receptor binding affinity measurement in cell-free systems
  • ●Binding-protein affinity comparison against the native sequence
  • ●Analytical reference standard for identity confirmation

All compounds sold by Lumo are intended strictly for in vitro research and laboratory use only. These products are NOT intended for human consumption, medical, veterinary, or household use. By purchasing from Lumo, you acknowledge that you are a qualified researcher or institution and will use these products solely for research purposes in compliance with all applicable laws and regulations.

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